Deaf or dead? Better drugs needed to stop drug-resistant TB
This has emerged as one of the key issues at the third South African tuberculosis conference, which opened last night (Tues) in Durban.
At present, people with drug-resistant TB face almost two years’ of treatment, including a daily injection for the first six months.
Despite this punishing regimen, less than half the cases of drug-resistant TB were cured in South Africa last year, according to the World Health Organisation. A number of patients also stop treatment because they cannot tolerate the side effects.
‘Treatment for drug-resistant TB is ineffective. It is too long, there are significant side-effects and it is expensive,’ according to Dr Helen Cox of Medicins sans Frontieres.
‘Aside from the daily injections that are very painful, 30 percent of people with drug-resistant TB develop hearing loss that is irreversible as a side-effect of the drugs,’ said Cox.
‘If someone starts going deaf a few weeks into treatment, what do we do? They need to continue with their treatment, but this means they will either be deaf or dead. This highlights the urgent need for new drugs.’
The Treatment Action Campaign, Section27 and Oxfam, called for patients with drug-resistant TB who were failing to respond to treatment to be given ‘access to the best available medicines’.
The organisations argued for such patients to get compassionate access to new, promising medicines not yet approved by the Medicines Control Council, including Linezolid, Bedaquiline and Delaminid.
The organisation delivered a memorandum containing five demands to conference organisers shortly before the opening.
Other demands include the diagnosis of all people living with TB and the decentralisation of care for people with drug-resistant TB, enabling them to be treated at home instead of hospitalised for long periods.
Health Minister Aaron Motsoaledi was due to open the conference but had to withdraw at the last minute to attend ‘urgent business’, possibly linked to the Cabinet reshuffle.
Meanwhile, speaker Professor Valerie Mizrahi from the University of Cape Town, said the world was in an exciting ‘new era of TB drug discovery’, but that overcoming TB was formidable as the bacteria had the ability to ‘persist’ in the face of treatment.
Bringing a personal touch to the opening ceremony, Dr Ausi Nkhi told the 1 700 delegates how she had contracted TB of the uterus as a medical student. As a result, she had been unable to fall pregnant and had endured four ectopic pregnancies.
Nkhi warned that healthworkers faced significant more risk of getting TB than the general population.
‘I am living with the aftermath of TB and I wish that no one should go through suffering and death as a result of this disease,’ said Nkhi.
Click here to view the conference presentations.
Author
Health-e News is South Africa's dedicated health news service and home to OurHealth citizen journalism. Follow us on Twitter @HealtheNews
Republish this article
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
Unless otherwise noted, you can republish our articles for free under a Creative Commons license. Here’s what you need to know:
You have to credit Health-e News. In the byline, we prefer “Author Name, Publication.” At the top of the text of your story, include a line that reads: “This story was originally published by Health-e News.” You must link the word “Health-e News” to the original URL of the story.
You must include all of the links from our story, including our newsletter sign up link.
If you use canonical metadata, please use the Health-e News URL. For more information about canonical metadata, click here.
You can’t edit our material, except to reflect relative changes in time, location and editorial style. (For example, “yesterday” can be changed to “last week”)
You have no rights to sell, license, syndicate, or otherwise represent yourself as the authorized owner of our material to any third parties. This means that you cannot actively publish or submit our work for syndication to third party platforms or apps like Apple News or Google News. Health-e News understands that publishers cannot fully control when certain third parties automatically summarise or crawl content from publishers’ own sites.
You can’t republish our material wholesale, or automatically; you need to select stories to be republished individually.
If you share republished stories on social media, we’d appreciate being tagged in your posts. You can find us on Twitter @HealthENews, Instagram @healthenews, and Facebook Health-e News Service.
You can grab HTML code for our stories easily. Click on the Creative Commons logo on our stories. You’ll find it with the other share buttons.
If you have any other questions, contact info@health-e.org.za.
Deaf or dead? Better drugs needed to stop drug-resistant TB
by Health-e News, Health-e News
June 13, 2012